Vasopressin Increases Cerebral Perfusion Pressure but not Cerebral Blood Flow in Neurosurgical Patients with Catecholamine-Refractory Hypotension: A Preliminary Evaluation Using the Non-Invasive Quantix ND in Comparison to the Literature

The means of treatment of ICU patients is to sustain perfusion and O2 delivery to all major organs to avoid organ damage. On neurosurgical ICU the most important factor is to prevent secondary brain injury after traumatic brain injury (TBI) or subarachnoid hemorrhage (SAH) due to ischemia or low tissue oxygenation. To minimize the risk of brain ischemia, standard treatment guidelines have been established including the maintenance of a minimum cerebral perfusion pressure (CPP). The management of CPP normally includes the control of intracerebral pressure (ICP) and mean arterial pressure (MAP), since CPP= MAP-ICP. Despite many clincial trials so far no level I evidence for an ideal CPP exists, but the guidelines of the Brain Vasopressin Increases Cerebral Perfusion Pressure but not Cerebral Blood Flow in Neurosurgical Patients with Catecholamine-Refractory Hypotension: A Preliminary Evaluation Using the Non-Invasive Quantix ND in Comparison to the Literature